Journal
Longevity & Performance Research
Notes from the practice on longevity, performance, peptides, and evidence-based protocols.
5 Supplements I'd Get Right Before Starting Peptides
Peptides are having a moment. Every week someone asks me which one they should start with — BPC-157, CJC/Ipamorelin, a GLP-1, something for recovery. And my answer is almost always the same: What does your supplement stack look like right now?
Sean P. Carr, CISSN, NBC-HWC · September 10, 2026
The Clock Inside Every Cell Runs on Vitamins — And More Isn't Always Better
New research shows your circadian rhythm and your methylation cycle are, at the molecular level, the same system. Understanding why changes how you should think about B-vitamins, choline, and popular supplements like SAMe.
Sean P. Carr, CISSN, NBC-HWC · July 5, 2026
Optimization or Enhancement? Where the Line Actually Falls
For most of modern history, the tools that fine-tune human hormones lived behind a velvet rope. Elite athletes had team physicians. The wealthy had concierge endocrinologists. Everyone else got a five-minute appointment, a "your levels are normal," and a shrug.
Sean P. Carr, CISSN, NBC-HWC · June 28, 2026
Why I Treated My Heart Like a Longevity Investment, with a Cleerly CCTA Scan
What Cleerly adds is the part that matters most. It's an FDA-cleared, AI-driven platform that analyzes those CCTA images and builds a **3D model of your coronary arteries** — then quantifies and characterizes the plaque inside them. It doesn't just tell you *whether* an artery is narrowed. It measures **how much plaque you have, where it is, and — critically — what kind it is.**
Sean P. Carr, CISSN, NBC-HWC · June 17, 2026
Can Psychedelics Calm Chronic Inflammation?
But there's a second story unfolding in the same laboratories, and almost no one outside of pharmacology is talking about it. It has nothing to do with mystical experiences or ego dissolution. It's about something far more ordinary, and in many ways far more consequential for how most people age: inflammation.
Sean P. Carr, CISSN, NBC-HWC · June 13, 2026
